Peter's brother works for a big, new biotech company that's based out of Honolulu. Of course, all is not right with them, especially the obviously villainous CEO. Peter and a group of young scientists are offered jobs--and they go to the island--but Peter's brother is killed in boating accident. This company is up to something, which has to do with the military, and the big secret project is that they have the technology to shrink things down to a very small size. Including weapons--and humans to operate them. But there's a drawback--after a few days the shrunken people become sick and die (which has to do with a problem with the blood molecules/gravity). Peter and his group are shrunken down, escape to the nearby jungle, and have to somehow survive predatory insects--and soldiers--until they can figure out a way to get back to their normal size.
This is my least favorite Michael Crichton book, especially when compared to STATE OF FEAR and NEXT. It seems too much like an overwritten screenplay, not a novel. It's like a humorless, adult version of HONEY, I SHRUNK THE KIDS.