A doctor (Billy Zane) who is in Brazil for a conference gets called in by the doctors at a local hospital to look at a patient's MRI. He has tumors in all the exact spots where memory is stored, which is very unlikely to occur. The patient is a "John Doe" and covered in a red substance one of the native tribes use in their rituals. The doctor comes in to contact with this substance when there's a rip in his latex glove - and is affected by these intense daydreams and nightmares, which turn out to be memories. Just whose memories they are is the crux of the story.
He learns that the man in the hospital was an anthropologist doing a paper on this tribe and that this powder contains a substance from the human pituitary gland and is a strong hallucigen. Part of the doctor's visions consist of a child killer, who makes casts of their faces. Is his father, who supposedly died before he was born, a killer? And who is stalking him now as he gets closer to the truth?
This movie has a great cast, with Ann Margret and Tricia Helfer (new BATTLESTAR GALACTICA but Zane can't quite carry the movie and his wig was fairly distracting.