Chase Masterson is quite good here (and looks hot in leather, riding a motorcycle), portraying sort of the opposite of her Leeta character from DEEP SPACE NINE. She's a scientist who has created a man/lizard hybrid in hopes of defeating death, but the creature has gotten away and starts killing people out in the countryside.
A group of friends, who have not seen each other since the death of one of their peers years before, reunite at the cabin where he was last seen alive. Unfortunately, this is near where the creature is stalking. Maggie Grace (LOST, FOG remake) is an amazingly beautiful actress but can't act worth a damn (hint, someone cast her in a movie as a deaf-mute or something, it'll improve her performance).
The makeup effects of the lizard man are good, as should be expected as effects artist Mark Burchett directed the movie but as is the case with the majority of low-budget horror movies nowadays, the script is lacking.