This starts at a mental asylum, where the severe inbred humans are kept. They escape, but not before they dismember the staff. The main doctor is hoisted up by wires and pulled apart. Years later a group of friends go snowmobiling on their winter break and come across the abandoned facility during a storm. It's not deserted, of course, but still inhabited by these hillbilly mutants. They are killed one by one. Brutal, good prequel that sets up the series rest of the series and tie directly to Wrong Turn 5. However, I kept on thinking "Do they get blizzards in Virginia?", where this takes place?